William Carpenter, M.D., a professor of psychiatry and pharmacology at the University of Maryland School of Medicine, agreed. However, Kane pointed out, major concerns regarding the use of this technology are likely to arise, such as how the information obtained by the device will be protected. “The technology can provide important advances in addressing highly prevalent problems in patients adhering to medications,” Kane told Psychiatric News. The most common adverse event was minor skin irritation that occurred at the site of the wearable sensor.
Of those who completed the study, 70 percent reported the software for the medical device to be easy to understand 89 percent considered the device to be useful to them in terms of adherence. The results, published in the Journal of Clinical Psychiatry in 2013, showed that 27 out of 28 people completed the study.
The pilot study consisted of 28 patients with bipolar disorder or schizophrenia. John Kane, M.D., a professor of psychiatry at the Zucker Hillside Hospital and the Hofstra North Shore-LIJ School of Medicine, conducted a pilot study with the antipsychotic/medical device. With the ingestible sensor, “we can actually tell that the patient ingested the pill and not just punched it out of a card or removed the cap of the pill bottle.” “The ingestible sensor measures medication-taking patterns and physiological response of the patient,” said Timothy Peters Strickland, M.D., a psychiatrist and senior director of Global Clinical Development at Otuska.
Patients as well as physicians and caregivers-with the patient’s consent-can view the information using a secure web portal. Such information can then be transmitted to a patient’s mobile phone or Bluetooth device. The patch records and time stamps information from the ingestible sensor in addition to collecting other patient metrics, including rest and activity patterns. The modified Abilify tablet contains an ingestible sensor that communicates with a sensor patch worn by the patient and medical software application.
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